Prof. Dr. med. Joachim P. Steinbach

Prof. Dr. med. Joachim P. Steinbach

Neurologist

Graduation, Post Graduation

University Hospital Frankfurt am Main, Frankfurt – Germany University Hospital Frankfurt am Main, Frankfurt – Germany

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About Prof. Dr. med. Joachim P. Steinbach

Prof. Dr. med. Joachim P. Steinbach is an internationally renowned German Senior Neurologist and Neuro-Oncologist based in Frankfurt, widely recognised as a leading Neurologist specialist in Frankfurt, Germany for glioma, glioblastoma, brain tumours, astrocytoma, stroke, multiple sclerosis, neuro-oncology immunotherapy, IDH-mutant glioma, and ERGO calorie-restricted ketogenic trials.

  • 27+ years of clinical and academic experience in neurology and neuro-oncology
  • Medical Studies (Graduation) in Germany
  • Post Graduation — Habilitation in Neurologie at Universität Tübingen, November 2005
  • Facharzt für Neurologie (Board-Certified Specialist in Neurology), 2002
  • Hertie-Stiftungsprofessur für Neuroonkologie (Hertie Foundation Professor of Neuro-Oncology)
  • Currently Leiter (Director) of Dr. Senckenbergisches Institut für Neuroonkologie at Klinikum der J.W. Goethe-Universität Frankfurt, since January 1, 2008
  • 246-335 publications, 14,835 citations
  • Alfred-Vogt-Preis recipient
  • Investigator on landmark IDH1 vaccine trial (Nature, 2021)

Qualifications & Credentials

Medical Degrees

  • Medical Studies (Medizinstudium / Graduation) — Germany
  • Post Graduation — Habilitation in Neurologie, Universität Tübingen, November 2005
  • Facharzt für Neurologie (Board-Certified Specialist in Neurology) — 2002
  • Hertie-Stiftungsprofessur für Neuroonkologie (Hertie Foundation Professor of Neuro-Oncology), since 2008

Fellowships & Special Training

  • Wissenschaftlicher Assistent (Scientific Assistant) at Institut für Neuropathologie, Universitätsspital Zürich, Switzerland
  • Wissenschaftlicher Assistent at Neurologische Klinik, Universität Tübingen
  • Wissenschaftlicher Assistent at Universitätsklinik für Psychiatrie und Psychotherapie, Tübingen
  • Specialised training in Neuro-Oncology
  • Specialised training in Glioma and Glioblastoma Management
  • Specialised training in Brain Tumour Multidisciplinary Care
  • Specialised training in CAR-NK Cell Immunotherapy for Brain Tumours
  • Specialised training in Oncolytic Virotherapy
  • Specialised training in Calorie-Restricted Ketogenic Diet (ERGO trials)
  • Specialised training in IDH-Mutant Glioma Targeted Therapy

Certifications & Accreditations

  • German Medical Association (Bundesärztekammer) — Registered
  • Hessische Landesärztekammer (Hessian Medical Association) — Registered
  • Facharzt für Neurologie (Board-Certified Specialist in Neurology), 2002
  • Habilitation Qualification — Universität Tübingen, 2005
  • Hertie-Stiftungsprofessur für Neuroonkologie
  • Member — Deutsches Konsortium für Translationale Krebsforschung (DKTK)

Areas of Expertise

Major Conditions Treated

  • Glioma (Low-Grade and High-Grade)
  • Glioblastoma (GBM)
  • Astrocytoma
  • Oligodendroglioma
  • IDH-Mutant Glioma
  • Brain Metastases
  • Meningioma
  • Skull Base Tumours
  • Recurrent Brain Tumours
  • Primary CNS Lymphoma
  • Stroke (Ischemic & Haemorrhagic)
  • Multiple Sclerosis (MS)
  • Pediatric Neuro-Oncology
  • Status Epilepticus in Brain Tumour Patients
  • Gliomatosis Cerebri-like Glioma (GCLG, IDH-Wildtype)
  • Neurofibroma / Schwannoma Hybrid Nerve Sheath Tumours

Professional Experience

Current Affiliation

  • Dr. Senckenbergisches Institut für Neuroonkologie, Zentrum der Neurologie und Neurochirurgie, Klinikum der J.W. Goethe-Universität Frankfurt — Leiter (Director), since January 1, 2008
  • J.W. Goethe-Universität Frankfurt — Hertie-Stiftungsprofessur für Neuroonkologie, since 2008
  • Address: Schleusenweg 2-16, 60528 Frankfurt am Main, Germany
  • Member — Deutsches Konsortium für Translationale Krebsforschung (DKTK)

Past Affiliations

  • Universitätsklinik Tübingen, Neurologische Klinik — Oberarzt (Senior Physician), since November 2005
  • Verbundvorhaben "Gliome: Interdisziplinäre Neuroonkologie, molekulare Diagnostik und neue Therapieansätze" (Deutsche Krebshilfe-funded) — Ärztlicher Koordinator (Medical Coordinator), since October 2004
  • Comprehensive Cancer Centers Tübingen, Zentrum für Neuroonkologie — Ärztlicher Koordinator (Medical Coordinator), since 2003
  • Universitätsklinik für Psychiatrie und Psychotherapie, Tübingen — Wissenschaftlicher Assistent (Past)
  • Neurologische Klinik, Universität Tübingen — Wissenschaftlicher Assistent (Past)
  • Institut für Neuropathologie, Universitätsspital Zürich, Switzerland — Wissenschaftlicher Assistent (Past)

Academic & Research Roles

  • Leiter (Director) — Dr. Senckenbergisches Institut für Neuroonkologie at Klinikum der J.W. Goethe-Universität Frankfurt, since January 1, 2008
  • Hertie-Stiftungsprofessur für Neuroonkologie
  • Investigator-Initiated Trials (IIT) Coordinator — CAR2BRAIN trial (genetically modified NK cells for glioblastoma recurrence)
  • Investigator-Initiated Trials Coordinator — XVir trial (recombination-competent oncolytic virus for glioblastoma recurrence)
  • Investigator-Initiated Trials Coordinator — ERGO trials (nutritional therapies / calorie-restricted ketogenic diet)
  • Co-Investigator — Landmark IDH1 vaccine trial (Nature, 2021)
  • Author — 246-335 scientific publications, 14,835 citations
  • Active speaker — National and international neurology and neuro-oncology conferences
  • Member — Multiple research collaborations with Georg-Speyer-Haus and Blutspendedienst Hessen

Key Achievements

  • 27+ years of clinical and academic experience
  • Currently Leiter (Director) of Dr. Senckenbergisches Institut für Neuroonkologie at Klinikum der J.W. Goethe-Universität Frankfurt since January 1, 2008
  • Hertie-Stiftungsprofessur für Neuroonkologie holder
  • 246-335 scientific publications with 14,835 citations
  • Author of landmark IDH1 vaccine paper in Nature (2021) — Platten M, Bunse L, Wick A et al. "A vaccine targeting mutant IDH1 in newly diagnosed glioma."
  • Investigator-Initiated Trials Coordinator: CAR2BRAIN, XVir, ERGO
  • Habilitation in Neurologie, Universität Tübingen, 2005
  • Facharzt für Neurologie, 2002
  • Past Ärztlicher Koordinator at Comprehensive Cancer Centers Tübingen
  • Alfred-Vogt-Preis recipient
  • Member of Deutsches Konsortium für Translationale Krebsforschung (DKTK)

Awards & Recognitions

National & International Awards

  • Alfred-Vogt-Preis
  • Hertie-Stiftungsprofessur für Neuroonkologie (Hertie Foundation Professorship in Neuro-Oncology)
  • Habilitation Qualification — Universität Tübingen, November 2005

Professional Memberships

  • German Society for Neurosurgery (DGNC) — Member
  • German Society for Basic Skull Surgery — Member
  • Deutsche Gesellschaft für Neurologie (DGN) — Member
  • Deutsche Krebsgesellschaft (German Cancer Society) — Member
  • Deutsche Gesellschaft für das Studium des Schmerzes — Member
  • Deutsches Konsortium für Translationale Krebsforschung (DKTK) — Member
  • Hessische Landesärztekammer — Registered
  • German Medical Association (Bundesärztekammer) — Registered

Research & Publications

Published Papers (Selected)

  • Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W. "A vaccine targeting mutant IDH1 in newly diagnosed glioma." Nature. 2021 Apr; 592(7854):463–468.
  • Ronellenfitsch MW, Harter PN, Kirchner M, Heining C, Hutter B, Gieldon L, Schittenhelm J, Schuhmann MU, Tatagiba M, Marquardt G, Wagner M, Endris V, Brandts CH, Mautner VF, Schröck E, Weichert W, Brors B, von Deimling A, Mittelbronn M, Steinbach JP, Reuss DE, Glimm H, Stenzinger A, Fröhling S. "Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors." J Clin Invest. 2020 May 1; 130(5):2488–2495.
  • Strecker MI, Wlotzka K, Strassheimer F, Roller B, Ludmirski G, König S, Röder J, Opitz C, Alekseeva T, Reul J, Sevenich L, Tonn T, Wels WS, Steinbach JP, Buchholz CJ, Burger MC. "AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma." Oncoimmunology. 2022 Oct 11; 11(1):2127508.
  • Steinbach JP et al. "Increased occurrence of status epilepticus in patients with brain metastases and checkpoint inhibition." Nov 2020.
  • Steinbach JP et al. "Maintenance of Energy Homeostasis during Calorically Restricted Ketogenic Diet and Fasting — MR-Spectroscopic Insights from the ERGO2 Trial."

Ongoing Research & Clinical Interests

  • Glioma and glioblastoma treatment resistance mechanisms
  • CAR2BRAIN trial — genetically modified NK cells for glioblastoma recurrence
  • XVir trial — recombination-competent oncolytic virus for glioblastoma
  • ERGO trials — calorie-restricted ketogenic diet and metabolic therapy
  • IDH1 vaccine for newly diagnosed glioma
  • HER2-targeted CAR-NK cells for glioblastoma
  • AAV-mediated gene transfer of checkpoint inhibitors
  • Tumour microenvironment and stress pathways
  • Brain biopsy diagnostics and tumour heterogeneity
  • Functional connectivity in gliomas (imaging biomarker)
  • Plasma lipidomic and metabolomic profiles in high-grade glioma
  • Targetable ERBB2 mutations in nerve sheath tumours

Estimated Treatment Costs

Procedure / ConsultationEstimated Cost (INR)Estimated Cost (USD)
Neurology / Neuro-Oncology Consultation (Germany)₹15,000 – ₹35,000$180 – $420
Brain Tumour Biopsy (Stereotactic)₹6,00,000 – ₹14,00,000$7,200 – $16,800
Glioblastoma Multidisciplinary Care (per cycle)₹3,50,000 – ₹10,00,000$4,200 – $12,000
Targeted Therapy / Immunotherapy (per cycle)₹2,50,000 – ₹8,00,000$3,000 – $9,600
Clinical Trial Enrollment (CAR2BRAIN / XVir / ERGO)Per Trial ProtocolPer Trial Protocol
Comprehensive Brain Tumour Care Package₹14,00,000 – ₹35,00,000$16,800 – $42,000

*Indicative estimates only. Actual costs subject to hospital pricing, case complexity, and insurance. Contact Cancer Rounds for a personalised quote.

Frequently Asked Questions

1. What advanced technologies does Prof. Dr. med. Joachim P. Steinbach use in Neurologist treatment?

Prof. Dr. med. Joachim P. Steinbach uses advanced glioma and glioblastoma multidisciplinary care, modern IDH1 vaccine therapy (Nature 2021), comprehensive CAR2BRAIN trial CAR-NK cell immunotherapy for glioblastoma recurrence, integrated XVir oncolytic virotherapy trial, modern ERGO calorie-restricted ketogenic diet trials, comprehensive AAV-mediated gene transfer of checkpoint inhibitors with HER2-targeted CAR-NK cells, integrated targeted therapy for IDH-mutant glioma, modern targetable ERBB2 mutation therapy for nerve sheath tumours, comprehensive stereotactic brain biopsy, integrated multidisciplinary tumour board coordination, modern stroke management, comprehensive multiple sclerosis care, integrated neuro-imaging biomarker research, modern functional connectivity imaging, and Phase I–IV clinical trial coordination — a cutting-edge translational toolkit refined through Universität Tübingen Habilitation training and Comprehensive Cancer Centers experience that establishes him as a leading neurologist specialist in Frankfurt, Germany.

2. What conditions does Prof. Dr. med. Joachim P. Steinbach specialize in treating?

Prof. Dr. med. Joachim P. Steinbach specialises in glioma (low-grade and high-grade), glioblastoma (GBM), astrocytoma, oligodendroglioma, IDH-mutant glioma, brain metastases, meningioma, skull base tumours, recurrent brain tumours, primary CNS lymphoma, stroke (ischemic & haemorrhagic), multiple sclerosis (MS), pediatric neuro-oncology, status epilepticus in brain tumour patients, gliomatosis cerebri-like glioma (GCLG, IDH-wildtype), and neurofibroma / schwannoma hybrid nerve sheath tumours — comprehensive neuro-oncology and neurology care for international patients seeking best neuro-oncology in Germany.

3. How do I book an appointment with Prof. Dr. med. Joachim P. Steinbach?

Appointments with Prof. Dr. med. Joachim P. Steinbach can be booked directly through the Cancer Rounds website or by contacting their international patient department for priority scheduling.

4. Can international patients receive treatment from Prof. Dr. med. Joachim P. Steinbach?

Yes. Cancer Rounds provides full assistance for international patients seeking treatment from Prof. Dr. med. Joachim P. Steinbach, including medical visa invitation letters, airport transfers, and local accommodation coordination.

5. What support is available for international patients?

International patients benefit from a dedicated concierge service provided by Cancer Rounds, including language interpretation, financial counselling, and pre-travel virtual consultations to review medical records before arrival.

6. Does Prof. Dr. med. Joachim P. Steinbach offer second opinions for Neurologist cases?

Yes. Second opinion consultations can be arranged via Cancer Rounds for patients who wish to review their diagnosis or treatment plan with an expert neurologist specialist in Frankfurt, Germany, especially for complex glioblastoma (CAR2BRAIN / XVir trial candidate), IDH-mutant glioma (vaccine candidate), recurrent brain tumours, ERGO ketogenic trial candidate, and rare nerve sheath tumour cases.

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