Aplastic Anemia Archives - Cancer Rounds

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2nd
Feb 2022

Going For A Bone Marrow Transplant- Must Be Aware of Certain Verities

Bone Marrow Treatment

Bone marrow treatment in India is an attraction for the bulk of medical tourists due to experts and experienced eminent Oncologists in India.

The Cancer Rounds is also helping individuals seeking bone marrow treatment in India that are also from nations and different regions worldwide. 

During the bone marrow treatment, the bone marrow transplant procedure performed is targeted with the goal to replace bone marrow that has been damaged or destroyed by disease, infection, or chemotherapy.

This procedure of bone marrow transplant involves transplanting blood stem cells, which travel to the bone marrow where they produce new blood cells and promote the growth of new marrow cells that are healthy. 

 

What is bone marrow?

Bone marrow is the spongy, fatty tissue inside human bones. It creates important parts of the blood- for instance, red blood cells, which carry oxygen and nutrients throughout the body, white blood cells, which fight infection, and platelets, which are responsible for the formation of clots. 

Bone marrow contains immature blood-forming stem cells known as hematopoietic stem cells or HSCs. The mentioned stem cell is considered a predecessor for differentiated cells.

These stem cells are unspecialized, meaning they have the potential to multiply through cell division and either remain stem cells or differentiate and mature into many different kinds of blood cells. The HSC found in the bone marrow will make new blood cells throughout a lifespan of an individual. 

 

The Procedure of Bone Marrow Transplant

the target is to replace your damaged stem cells with healthy cells. This helps your body make enough white blood cells, platelets, or red blood cells to avoid infections, bleeding disorders, or anaemia. Healthy stem cells can come from a donor, or they can come from the patient’s own body.

In such cases, stem cells can be harvested, or grown, before you start chemotherapy or radiation treatment and genetically engineered in the lab. Those healthy cells are then stored and used in transplantation. 

 

Why Do You Need Bone Marrow Transplant?

The need for Bone marrow transplants, performed when a person’s marrow isn’t healthy enough to function properly is justified.  This could be due to chronic infections, disease, or cancer treatments. Some reasons for a bone marrow transplant include: 

  • aplastic anaemia, – a disorder in which the marrow stops making new blood cells 
  • cancers that affect the marrow, such as leukaemia, lymphoma, and multiple myeloma 
  • damaged bone marrow due to chemotherapy 
  • congenital neutropenia, – an inherited disorder that causes recurring infections 
  • sickle cell anaemia, – an inherited blood disorder that causes misshapen red blood cells 
  • thalassemia, – an inherited blood disorder where the body makes an abnormal form of haemoglobin, an integral part of red blood cells 
  • multiple sclerosis- a disease in which the immune system eats away at the protective covering of nerves 

 

Before Transplant

As Bone marrow transplants take up to a week and it is advised that the successful arrangements before your first transplant session as directed by your treating doctor are made up to mark. These can include: 

  • housing near the hospital for your loved ones 
  • insurance coverage, payment of bills, and other financial concerns 
  • care of children or pets 
  • taking a medical leave from work 
  • packing clothes and other necessities 
  • arranging travel to and from the hospital 

 

During Bone Marrow Transplant

During bone marrow treatment, your immune system will be compromised, affecting its ability to fight infections. Therefore, you’ll stay in a special section of the hospital that’s reserved for people receiving bone marrow transplants.

This reduces your risk of being exposed to anything that could cause an infection. Also to boost immunity the diet will be given to you by your treating team. At this stage communicate with your doctor without hesitation. 

During this time, you’ll be closely monitored for any complications or any side effects – so you can get a solution for the issue you meet the solution. 

Current innovations in bone marrow treatment in India are all availed at cancer rounds with partnered best oncologists. 

 

Posted by, magneto
February 2, 2022
1st
Feb 2022

Aplastic Anemia With Emphasis On The Treatment Options

Aplastic Anemia

Aplastic anemia occurs when human body stops producing enough new blood cells. The condition leaves the individual fatigued and more prone to infections and uncontrolled bleeding. Aplastic anemia can be short-lived, or it can become chronic. It can be severe and even fatal. It less common and serious condition, which can develop at any age. Aplastic anemia can occur suddenly, or it can come on slowly and worsen over time. Clinically presented as mild or severe.

Aplastic anemia can have no symptoms but if present, signs and symptoms can include:

1. Fatigue

2. Shortness of breath

3. Rapid or irregular heart rate

4. Pale skin

5. Frequent or prolonged infections

6. Unexplained or easy bruising

7. Nosebleeds and bleeding gums

8. Prolonged bleeding from cuts

9. Skin rash

10. Dizziness

11. Headache

12. Fever

The following tests can help diagnose aplastic anemia in the designed diagnostic workup for Aplastic anemia:

Blood tests include complete blood cell count – In aplastic anemia all three of these blood cell levels are low.

Bone marrow biopsy is done by a needle to remove a small sample of bone marrow from a large bone in your body, such as your hipbone. The sample is examined under a microscope to rule out other blood-related diseases. In aplastic anemia, bone marrow contains fewer blood cells than normal.

Treatment provided for aplastic anemia by Top hematologists in Gurgaon is dependent on the severity of condition and demographic details like age.

The treatment options include: observation, blood transfusions, medications, or bone marrow transplantation. Severe aplastic anemia, in which your blood cell counts are extremely low, is life-threatening and requires immediate hospitalization.

Blood transfusions: not cure for aplastic anemia, blood transfusions control bleeding and relieve symptoms by providing blood cells in patient’s bone marrow that isn’t producing. While there’s generally no limit to the number of blood transfusions but complications can sometimes arise with multiple transfusions.

Stem cell transplant: done to rebuild the bone marrow is considered to be the only successful treatment option for people with severe aplastic anemia. A stem cell transplant, also called a bone marrow transplant, is generally the treatment of choice in younger patients.

Immunosuppressants is preferred in cases who can’t undergo a bone marrow transplant or for those whose aplastic anemia is due to an autoimmune disorder. In this the treatment can involve drugs that alter or suppress the immune system (immunosuppressants). Drugs such as cyclosporine (Gengraf, Neoral, Sandimmune) and anti-thymocyte globulin suppress the activity of immune cells that are damaging bone marrow. This helps bone marrow recover and generate new blood cells. Corticosteroids, such as methylprednisolone (Medrol, Solu-Medrol), are often used with these drugs.

Bone marrow stimulants in verities that are including colony-stimulating factors, such as sargramostim (Leukine), filgrastim (Neupogen) and pegfilgrastim (Neulasta), epoetin alfa (Epogen/Procrit), and eltrombopag (Promacta). These drugs help stimulate the bone marrow to produce new blood cells

Antibiotics, antivirals are administered in cases of aplastic anemia. Because the condition has weakens]ed your immune system, which leaves you more prone to infections.

Other treatments for Aplastic anemia caused by radiation and chemotherapy treatments for cancer usually includes follow up observations as it improves after those treatments stop. The same is true for most other drugs that induce aplastic anemia.

For more details please contact Cancer Rounds

Posted by, magneto
February 1, 2022
25th
Jan 2022

Bone Marrow Transplant Treatment and Its Treatment Team

bone marrow treatment in india

In our bones, spongy tissue is presently termed bone marrow which is responsible for the formation of blood cells. Yes, all blood cells are produced from “hematopoietic stem cells” or simple “stem cells” which are present in the bone marrow. A bone marrow transplant is a method to transfer healthy stem cells into a patient.

The special characteristics of the hematopoietic stem cell help them to renew themselves. Besides this, hematopoietic stem cells or stem cells in none marrow also can develop into any type of blood cells.

“Hematopoietic stem cell transplantation or bone marrow transplantation” is the technique that aids the injection of stem cells from bone marrow that produce red blood cells, white blood cells, and platelets into a recipient after a short course of chemotherapy called conditioning.

Before the process of Hematopoietic stem cell transplantation or bone marrow transplantation, the process of filtering stem cells is done and the goal of BMT is to transfuse healthy bone marrow cells in patients.

 

Advantages of Bone Marrow Transplant

Bone marrow transplant treatment is used successfully to treat diseases such as leukaemias, lymphomas, aplastic anaemia, immune deficiency disorders, multiple myeloma, etc.

 

There are two ways in which bone marrow transplant can be done, such as:

  • Autologous bone marrow transplant in which the donor is the patient himself or herself.
  • Allogeneic bone marrow transplant in which the donor shares the same genetic type as the patient.

 

Matching involves typing human leukocyte antigen (HLA) tissue. The antigens on the surface of these special white blood cells determine the genetic makeup of a person’s immune system.

There are antigens present in the blood. Around 100 HLA antigens are there from which few major antigens are supposed to match. If these HLA antigens of both the donor and recipient match then the transplant is possible. The others are considered “minor” and their effect on a successful transplant is not as well-defined.

Success in a bone marrow transplant procedure is the cure of a disease that is not achieved instantly.

Bone marrow transplant treatment is life-saving and in India the cost for BMT treatment range from about Rs. 15,00,000 to Rs.40,00,000.

 

Team of Bone Marrow Transplant Treatment

After knowing briefly about bone marrow transplant treatment, let us understand the role of the bone marrow transplant team:

The bone marrow transplant team is comprised of a group of specialists that work together for a successful transplant. The team consists of professionals specialized in oncology, haematology, immunology, and bone marrow transplantation.

Besides this, the role of the bone marrow transplant nurse coordinator who organizes all aspects of care provided before and after the transplant can never be forgotten.

As the bone marrow transplant nurse coordinator educates the patient, caregivers coordinate the diagnostic testing and are present for counselling during follow-up care.

It is necessary to take references before approaching the specialist. In this, you can collect information from social media, digital platforms, your relatives, and your family doctor.

 

How Cancer Rounds Can Help You?

Besides this our virtual hospital Cancer Rounds also provides a second opinion as well to ambulatory or remote cases who are hunting for the right bone marrow transplant specialist to proceed with.

Cancer Rounds is impregnated with the leading and the best cancer doctor in India, with the boon of both expertise and experience – here we also avail our patients to get their comments about those doctors before interacting with them.

Once you are satisfied proceed to read reviews of patient survivors’ stories available on the website that will surely answer your queries i.e. why the particular doctor is preferred for you.

 

  • Not always meet positive comments and doctors are also human, in case you come across some negative comments about their doctor, always scrutinize the comment because each case is different. This will give you an idea if it is a wise decision to go for the concerned specialist for Bone Marrow Transplant.

 

  • The bone marrow transplant specialist team in Cancer Rounds has strong experience with bone marrow transplants, as they are also updated to provide you with answers to queries like- what options do exist and how each one works for your situation.

 

  • The focus of Cancer Rounds is to reach far/remote patients as well, in this, we are guiding accommodation, and financial aids as well because the first thing you come across during treatment is that it’s not possible for patients during different phases of treatment to travel far away.

 

You can also contact us directly by sending us a query, in case you require a second opinion for a Bone marrow transplant for yourself or your loved being.

Posted by, Medical Team, Cancer Rounds
January 25, 2022

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