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Prof. Dr. Melanie Meyer-Luehmann

Neurologist

Prof. Dr. Melanie Meyer-Luehmann

Senior Consultant

years of experience
Diploma, Graduation
Freiburg University Hospital, Freiburg - Germany

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    Areas of Expertise

    Prof. Dr. Melanie Meyer-Luehmann

    Major Research & Clinical Areas

    • Alzheimer's Disease (Amyloid-Beta Plaque Formation & Seeding)
    • Neurodegeneration & Dementia
    • Neuroinflammation (Microglia in Neurodegeneration)
    • Adult Neurogenesis in Alzheimer's Disease
    • White Matter Integrity in Neurodegeneration
    • Cerebral Amyloidosis
    • Synaptic Dysfunction & Neuronal Loss

    Sub-specialties

    • Alzheimer's Disease Pathomechanisms (World-Leading Research): Prof. Meyer-Luehmann's landmark Nature publication (2008) — 'Rapid appearance and local toxicity of amyloid-beta plaques' — is among the most-cited works in Alzheimer's research worldwide. Her Science (2006) publication on exogenous induction of cerebral beta-amyloidogenesis established foundational knowledge of Alzheimer's seeding mechanisms — making her one of the world's foremost Alzheimer's disease researchers at Freiburg University Medical Center.
    • Microglia & Neuroinflammation: Expert in the role of microglia (brain immune cells) in regulating adult neurogenesis and contributing to Alzheimer's disease pathogenesis — including microglial propagation of amyloid-beta and neuroinflammatory mechanisms.
    • Functional CNS Restoration: Clinical and translational research focus on functional restoration in the CNS — including strategies to preserve or restore neurological function in Alzheimer's disease and other neurodegenerative conditions.

    Advanced Procedures & Treatments (Clinical)

    • Comprehensive Dementia Assessment & Diagnosis
    • Cognitive Neurology Consultation
    • Alzheimer's Disease — Diagnosis & Management
    • Memory Clinic Consultations
    • Advanced Neuroimaging (MRI, PET amyloid scanning)
    • Clinical Trial Participation (Alzheimer's Disease Therapies)

    Qualifications & Credentials

    Academic Degrees

    • Graduate Studies in Biology — University of Freiburg, Germany — 1993–1999
    • M.S. (Diplom) in Biology — University of Freiburg, Germany — 2000 (Thesis also at University of Michigan, Ann Arbor, USA with Prof. John Wayne Aldridge)
    • PhD in Neurobiology (summa cum laude) — University of Basel, Switzerland — 2000–2004 (with Prof. Mathias Jucker; Thesis: Experimental approaches to study cerebral amyloidosis in Alzheimer's disease)

    Fellowships & Special Training

    • Postdoctoral Fellow — Hertie Institute of Clinical Brain Research, Tübingen, Germany (with Prof. Mathias Jucker) — 2004–2005
    • Postdoctoral Fellow — Massachusetts General Institute for Neurodegenerative Disease (MIND), Harvard Medical School, Boston, USA (with Prof. Bradley T. Hyman) — 2005–2008
    • Independent Research Group Leader — Adolf-Butenandt-Institut, Ludwig-Maximilians-University (LMU) Munich — 2008–2011

    Certifications & Accreditations

    • Full Professor (W3) of Functional Restoration in CNS — Medical Center, University of Freiburg (since 2011)
    • Member — SFB 596 'Molecular Mechanisms of Neurodegeneration' (since 2009)
    • Member — Society for Neuroscience
    • Reviewer — Major international neuroscience and neurology journals

    Professional Experience

    Current Affiliation

    • Medical Center – University of Freiburg, Department of Neurology and Neurophysiology (Clinic for Neurology) — Full Professor (W3) & Head of Neurodegeneration Research Group (since 2011)

    Past Affiliations

    • Adolf-Butenandt-Institut, Ludwig-Maximilians-University (LMU) Munich — Independent Research Group Leader — 2008–2011
    • Massachusetts General Institute for Neurodegenerative Disease (MIND), Harvard Medical School, Boston, USA — Postdoctoral Fellow — 2005–2008
    • Hertie Institute of Clinical Brain Research, Tübingen, Germany — Postdoctoral Fellow — 2004–2005
    • University of Basel, Switzerland — PhD Training — 2000–2004

    Key Achievements

    • Emmy Noether Career Development Grant — Deutsche Forschungsgemeinschaft (DFG) — 2009 (highly competitive German research excellence award)
    • PhD (summa cum laude) — University of Basel — 2004
    • Postdoctoral Fellow — Harvard Medical School, Boston, USA — 2005–2008
    • Full Professor (W3) of Functional Restoration in CNS — Medical Center, University of Freiburg — since 2011
    • Landmark publications in Nature (2008) and Science (2006) on Alzheimer's disease pathomechanisms

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