Dr. Marwan Shaheen

Adult Hematology — Chronic Leukemia & Myeloproliferative Neoplasms

Dr. Marwan Shaheen

Consultant, chronic leukemia/ myeloproliferative neoplasms

20+ years of experience
MBBS; Residency in Internal Medicine; Fellowship in Hematology / Hematologic Malignancies (with Canadian training experience)
King Faisal Specialist Hospital, Riyadh - United Arab Emirates

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    Areas of Expertise

    Dr. Marwan Shaheen

    Major Conditions Treated

    • Chronic Myeloid Leukemia (CML)
    • Chronic Lymphocytic Leukemia (CLL)
    • Polycythemia Vera
    • Essential Thrombocythemia
    • Primary & Secondary Myelofibrosis
    • Myelodysplastic / Myeloproliferative Overlap Syndromes
    • Myelodysplastic Syndromes
    • Acute Myeloid Leukemia (Core Binding Factor & Other)
    • Philadelphia-Positive B-ALL
    • CML in Pregnancy

    Sub-specialties

    • Tyrosine Kinase Inhibitor Therapy for CML: Expert in imatinib, dasatinib, nilotinib, bosutinib, and ponatinib therapy for chronic myeloid leukemia, including treatment-free remission protocols — a trusted hematology specialist Riyadh, Saudi Arabia for chronic leukemia.
    • Myeloproliferative Neoplasms: Manages polycythemia vera, essential thrombocythemia, and myelofibrosis using JAK inhibitors (ruxolitinib, fedratinib), cytoreductive therapy, and HSCT referral.
    • Chronic Leukemia in Special Populations: Contributor to 15-year single-centre CML-in-pregnancy cohort and core binding factor AML consolidation research.

    Advanced Procedures & Treatments

    • Tyrosine Kinase Inhibitor Therapy (Imatinib, Dasatinib, Nilotinib, Bosutinib, Ponatinib)
    • JAK Inhibitor Therapy (Ruxolitinib, Fedratinib)
    • Cytoreductive Therapy (Hydroxyurea, Interferon) for MPN
    • BCL2 Inhibitor (Venetoclax) Combinations for CLL
    • BTK Inhibitor Therapy for CLL
    • Allogeneic HSCT Referral for Advanced MPN / MDS
    • Blinatumomab with TKI for Ph-Positive B-ALL
    • Molecular Monitoring for CML (BCR-ABL1 qPCR)

    Qualifications & Credentials

    Medical Degrees

    • MBBS
    • Residency — Internal Medicine

    Fellowships & Special Training

    • Fellowship — Hematology / Hematologic Malignancies
    • International training experience — Canadian academic medical centre

    Certifications & Accreditations

    • Saudi Commission for Health Specialties (SCFHS) Registration
    • Member — American Society of Hematology (ASH)
    • Member — European Hematology Association (EHA)

    Professional Experience

    Current Affiliation

    • King Faisal Specialist Hospital & Research Centre (KFSHRC), Riyadh, Saudi Arabia — Consultant, Chronic Leukemia / Myeloproliferative Neoplasms Section, Department of Hematology, Stem Cell Transplantation and Cellular Therapy (Present)

    Past Affiliations

    • University of Toronto / Princess Margaret Cancer Centre, Toronto, Canada — Research and clinical training experience (Past)

    Academic & Research Roles

    • Faculty — KFSHRC Hematology & HSCT Fellowship Programme
    • Member — KFSHRC Leukemia Multidisciplinary Tumour Board

    Key Achievements

    • Co-editor — Guidelines for the Management of Hematological Malignancies, KFSHRC Riyadh, 4th Edition (2015)
    • Contributing investigator — Saudi AML Whole-Genome Sequencing programme
    • Co-author on multi-centre research on blinatumomab + TKI for Ph+ B-ALL
    • Contributor to 15-year single-centre CML in pregnancy cohort analysis

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