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Dr. Syed Osman Ali Ahmed

Hematologist

Dr. Syed Osman Ali Ahmed

Consultant, Acute Leukemia (Adult Haematology / HSCT)

20+ years of experience

BSc (Hons), MBBS, MRCP, FRCPath — Imperial College London / UK-based medical training
King Faisal Specialist Hospital, Riyadh - United Arab Emirates

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    Areas of Expertise

    Dr. Syed Osman Ali Ahmed

    Major Conditions Treated

    • Acute Myeloid Leukemia (AML)
    • Acute Lymphoblastic Leukemia (ALL)
    • Chronic Myeloid Leukemia (CML)
    • Myelodysplastic Syndromes (MDS)
    • Core-Binding Factor Leukemia (t(8;21); RUNX1-RUNX1T1)
    • Fanconi Anemia (adult)
    • Aplastic Anemia
    • Dyskeratosis Congenita and Inherited Bone Marrow Failure

    Sub-specialties

    • Adult CAR-T Cell Therapy: Adult CAR-T Cell Lead at a regional centre of excellence — offering point-of-care in-house manufactured CAR-T, a first in Saudi Arabia.
    • Hematopoietic Stem Cell Transplantation: Expert in matched sibling, unrelated, and haploidentical transplants with post-transplant cyclophosphamide (PTCy) protocols.
    • Acute Leukemia Genomics & Precision Medicine: Lead investigator on the Saudi AML Genome Study, driving precision medicine approaches — key to best AML treatment in Saudi Arabia.

    Advanced Procedures & Treatments

    • Allogeneic Hematopoietic Stem Cell Transplantation
    • Autologous Stem Cell Transplantation
    • CD19 CAR-T Cell Therapy (in-house point-of-care manufactured)
    • Haploidentical HSCT with Post-Transplant Cyclophosphamide
    • AML Induction (7+3) and Consolidation Chemotherapy
    • Venetoclax-Based Regimens for AML
    • Inotuzumab Ozogamicin for Relapsed ALL
    • Sorafenib Maintenance Post-Transplant for FLT3-Mutated AML

    Qualifications & Credentials

    Medical Degrees

    • BSc (Hons) — Information not publicly available.
    • MBBS — Imperial College London, UK
    • MRCP — Royal College of Physicians, UK
    • FRCPath — Royal College of Pathologists, UK (Haematology)

    Fellowships & Special Training

    • Adult Haematology / HSCT — King Faisal Specialist Hospital & Research Centre, Riyadh

    Certifications & Accreditations

    • Member of the Royal College of Physicians (MRCP), UK
    • Fellow of the Royal College of Pathologists (FRCPath), UK
    • Saudi Commission for Health Specialties (SCFHS) registration

    Professional Experience

    Current Affiliation

    • King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia — Consultant, Adult Haematology / HSCT; Adult CAR-T Cell Lead (Current)

    Past Affiliations

    • Imperial College London, UK — Medical training
    • Information not publicly available.

    Academic & Research Roles

    • Adjunct Faculty — Alfaisal University, Riyadh
    • International collaborator — Eastern Mediterranean Blood and Marrow Transplantation Group (EMBMT)

    Key Achievements

    • 64+ indexed publications and 996+ citations
    • Principal investigator on the Saudi AML Genome Study (Blood 2024)
    • Lead clinician for Saudi Arabia's first large-scale point-of-care in-house CAR-T programme
    • Contributing author on WHO Eastern Mediterranean HSCT strategic priorities position paper

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