Memorial Hospitals Group, İstanbul – Turkey
About Prof. Semra KAHRAMAN
Prof. Dr. Dr. Semra Kahraman is an internationally respected Turkish IVF Specialist based in Istanbul, widely recognised as a leading IVF Specialist specialist in Istanbul, Turkey for pioneering ICSI, embryo freezing, PGT for single gene disorders, HLA typing, and aneuploidy testing in Turkey.
- 35+ years of clinical and academic experience in IVF and Reproductive Genetics
- Director, ART & Reproductive Genetics Unit, Istanbul Memorial Hospital since 2000
- First in Turkey to isolate and establish embryonic stem cell lines
- Past President of the PGT International Society (Preimplantation Genetic Diagnosis International Society)
- Multiple Lifetime Achievement Awards from Turkish Society of Reproductive Medicine and ASRM Star Awards (2017, 2018)
- 150+ scientific works and 738+ publications on infertility and reproductive genetics
Qualifications & Credentials
Medical Degrees
- Medical Doctor Training — Hacettepe University Medical School, Ankara, Turkey, 1973–1981
- Professional Training in Gynecology and Obstetrics — Faculty of Medicine, Ankara University, Ankara, Turkey, 1983–1989
- Assistant Professorship — Faculty of Medicine, Ankara University, Ankara, Turkey, 1994
- Full Professorship — Faculty of Medicine, Yeditepe University, Istanbul, Turkey, 2004
Fellowships & Special Training
- Haugesund Hospital Fertility Center & Oslo University Hospital Infertility Clinic, Norway, 1991–1992
- Weill Cornell's Center for Reproductive Medicine, New York, USA, 1996–1997
- Reproductive Genetic Institute (RGI), Chicago, USA, 1996–1997
- Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Vilvoorde, Belgium, 1996–1997
- Special Training — Cornell University IVF Center (USA), Rikshospitalet IVF Center (Norway)
Certifications & Accreditations
- Turkish Medical Association — Registered
- ESHRE-Accredited Professional (Istanbul Memorial Hospital IVF Laboratory)
- Full Professor — Faculty of Medicine, Yeditepe University, Istanbul
- Memorial Şişli Hospital IVF Laboratory — TÜRKAK Accreditation per ISO 15189 standards (first in Turkey)
Areas of Expertise
Major Conditions Treated
- Female Infertility
- Male Infertility & Severe Male Factor
- Recurrent Implantation Failure
- Recurrent Pregnancy Loss
- Low Ovarian Reserve
- Poor Ovarian Response
- Unexplained Infertility
- Advanced Maternal Age Infertility
- Single Gene Disorders (for PGT)
- HLA Matching Requirements
- Chromosomal Aneuploidies
- Recurrent Oocyte Maturation Defects (OOMD)
- Preimplantation Embryo Lethality (PREMBL)
Sub-specialties
- In Vitro Fertilization (IVF) & ICSI: Pioneer of ICSI in Turkey and comprehensive assisted reproductive technology — establishes her as a trusted IVF specialist specialist in Istanbul, Turkey.
- Preimplantation Genetic Testing (PGT-A, PGT-M, PGT-SR): Pioneer of PGT for single gene disorders, HLA typing, and aneuploidy testing in Turkey.
- Embryo Freezing / Vitrification: Pioneer of embryo freezing techniques in Turkey with multiple publications on vitrified blastocyst transfers.
- Reproductive Genetics & Embryonic Stem Cells: First in Turkey to isolate and establish embryonic stem cell lines — for international patients seeking best IVF and fertility treatment in Turkey.
- Time-Lapse Monitoring & AI-Assisted Embryo Selection: Research and clinical use of the CHLOE AI tool (Fairtility) for predicting euploidy.
- Andrology & Surgical Sperm Extraction: First in Turkey to perform microinjection and surgical sperm extraction.
Advanced Procedures & Treatments
- In Vitro Fertilization (IVF)
- Intracytoplasmic Sperm Injection (ICSI)
- Intrauterine Insemination (IUI)
- Embryo Vitrification & One-Step Warming
- Oocyte Freezing / Egg Freezing
- Fertility Preservation
- Preimplantation Genetic Testing for Aneuploidy (PGT-A)
- Preimplantation Genetic Testing for Monogenic Disorders (PGT-M)
- Preimplantation Genetic Testing for Structural Rearrangements (PGT-SR)
- HLA Typing for Embryos
- Whole-Exome Sequencing (WES) for OOMD & PREMBL
- Time-Lapse Embryo Monitoring (TLM)
- AI-Assisted Embryo Selection (CHLOE Tool)
- Surgical Sperm Extraction (TESE/MicroTESE)
- Frozen-Thawed Single Blastocyst Transfer
- Luteal Phase Support Protocols
Professional Experience
Current Affiliation
- Istanbul Memorial Hospital (Memorial Şişli Hospital), Istanbul, Turkey — Director of ART & Reproductive Genetics Unit, Since 2000
- Memorial Health Group — Managing Director of IVF and Genetics Center
- Memorial Şişli Hospital In Vitro Fertilization (IVF), Andrology and Genetics Center — Head
Past Affiliations
- Sevgi Hospital, Ankara — Director of ART (1993–2000)
- Ankara University, Faculty of Medicine — Assistant Professor (1994)
- Yeditepe University, Faculty of Medicine, Istanbul — Full Professor (2004)
- Weill Cornell's Center for Reproductive Medicine, New York, USA — Fellowship (1996–1997)
- Reproductive Genetic Institute (RGI), Chicago, USA — Fellowship (1996–1997)
- Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Belgium — Fellowship (1996–1997)
- Haugesund Hospital Fertility Center & Oslo University Hospital Infertility Clinic, Norway — Training (1991–1992)
- Ankara University Faculty of Medicine — OB/GYN Speciality Training (1983–1989)
- Hacettepe University Medical School — Medical Doctor Training (1973–1981)
Academic & Research Roles
- Full Professor — Faculty of Medicine, Yeditepe University, Istanbul (2004)
- Past President — Preimplantation Genetic Diagnosis International Society (PGDIS)
- Board Member — Preimplantation Genetic Diagnosis International Society
- Author — 150+ scientific works and 738+ publications on infertility, IVF, and reproductive genetics
- Invited Speaker and Chairman — Multiple international conferences including PGDIS, ASRM, ESHRE, and World Congress of Perinatal Medicine
- Researcher — Oxidative stress in IVF, recurrent pregnancy loss, time-lapse monitoring, AI in embryo selection
Key Achievements
- 35+ years of clinical and academic experience in IVF and reproductive genetics
- Pioneer of ICSI, embryo freezing, PGT for single gene disorders, HLA typing, and aneuploidy testing in Turkey
- First in Turkey to isolate and establish embryonic stem cell lines
- Past President of the PGT International Society
- Director of ART & Reproductive Genetics Unit at one of Turkey's largest IVF programs since 2000
- Published 150+ scientific works and 738+ publications on ResearchGate
- Memorial Şişli Hospital IVF Laboratory — first in Turkey to receive TÜRKAK Accreditation per ISO 15189
Awards & Recognitions
National & International Awards
- Scientific Encouragement Award for Work in Human Reproduction, 1996
- Scientific Encouragement Award for Work in Human Reproduction, 1997
- Lifetime Achievement Award — Turkish Society of Reproductive Medicine, 2008
- Lifetime Achievement Award — Bayburt Science Education and Culture Association, 2010
- Medical Travel Journal Awards — International Hospital of the Year (Department of Reproductive Medicine at Memorial Sisli Hospital), London, UK, 2015
- ASRM Star Award — American Society for Reproductive Medicine, 2017
- ASRM Star Award — American Society for Reproductive Medicine, 2018
Professional Memberships
- Preimplantation Genetic Diagnosis International Society (PGDIS) — Past President & Board Member
- European Society of Human Reproduction and Embryology (ESHRE) — Member
- American Society for Reproductive Medicine (ASRM) — Member
- Turkish Society of Reproductive Medicine — Lifetime Achievement Awardee
- Turkish Medical Association — Registered
Research & Publications
Published Papers (Selected)
- Kahraman S et al. "Improved clinical outcomes with one-step warming of vitrified blastocysts: a retrospective analysis of 3,167 transfers."
- Kahraman S et al. Research on embryo morphology, morphokinetic parameters, and time-lapse monitoring in women with recurrent pregnancy loss.
- Kahraman S et al. Research on whole-exome sequencing for infertile women due to recurrent oocyte maturation defects (OOMD) and/or preimplantation embryo lethality (PREMBL) — Istanbul Memorial Hospital, 2015–2021.
- Findikli N, Kahraman S, Akcin O, Sertyel S, Candan Z. "Establishment and characterization of new human embryonic stem cell lines." Reproductive Biomedicine Online 2005;10(5):617–627.
- Fiorentino F, Kahraman S, Karadayi H, Biricik A, Sertyel S, Karlikaya G, Saglam Y, Podini D, Nuccitelli A, Baldi M. "Short tandem repeats haplotyping of the HLA region in preimplantation HLA matching." European Journal of Human Genetics 2005;13(8):953–958.
- Kahraman S et al. Research on CHLOE AI tool (Fairtility) that predicts euploidy discriminating between morphokinetic behaviors of euploid and aneuploid blastocysts.
- Kahraman S et al. "Comparison of two vaginal progesterone formulations (Lutinus 100mg tablet and Crinone 8% gel) for luteal phase support in modified natural cycle frozen-thawed single blastocyst transfers."
- Kahraman S et al. "Artificial intelligence vs. manual morphology-based embryo selection in tested and non-tested cohorts: two prospective studies involving 934 IVF patients."
Ongoing Research & Clinical Interests
- Preimplantation genetic testing for aneuploidy (PGT-A)
- Controlled ovarian stimulation protocols
- Recurrent pregnancy loss and recurrent implantation failure
- Time-lapse monitoring and AI-assisted embryo selection
- Whole-exome sequencing in infertility
- Embryonic stem cell research
- Vitrified blastocyst transfer outcomes
Estimated Treatment Costs
| Procedure / Consultation | Estimated Cost (INR) | Estimated Cost (USD) |
|---|---|---|
| IVF / Fertility Consultation (Turkey) | ₹8,000 – ₹20,000 | $100 – $240 |
| Premium IVF/ICSI Package | ₹7,50,000 – ₹10,00,000 | $9,000 – $12,000 |
| Standard IVF/ICSI Cycle | ₹4,50,000 – ₹6,50,000 | $5,400 – $7,800 |
| Intrauterine Insemination (IUI) | ₹1,20,000 – ₹1,80,000 | $1,450 – $2,160 |
| Egg Freezing (incl. 1 year storage) | ₹1,00,000 – ₹1,40,000 | $1,200 – $1,680 |
| PGT-A / PGT-M / PGT-SR | ₹2,00,000 – ₹5,00,000 | $2,400 – $6,000 |
*Indicative estimates only. Actual costs subject to hospital pricing, case complexity, and insurance. Contact Cancer Rounds for a personalised quote.
Frequently Asked Questions
1. What advanced technologies does Prof. Semra KAHRAMAN use in IVF Specialist treatment?
Prof. Dr. Dr. Semra Kahraman uses advanced ICSI, embryo vitrification and one-step warming, PGT-A/PGT-M/PGT-SR, HLA typing for embryos, whole-exome sequencing for OOMD/PREMBL, time-lapse embryo monitoring, AI-assisted embryo selection with CHLOE tool (Fairtility), microTESE, and comprehensive fertility preservation — a cutting-edge toolkit that establishes her as a leading IVF specialist specialist in Istanbul, Turkey.
2. What conditions does Prof. Semra KAHRAMAN specialize in treating?
Prof. Dr. Dr. Semra Kahraman specialises in female and male infertility, severe male factor, recurrent implantation failure, recurrent pregnancy loss, low ovarian reserve, poor ovarian response, unexplained infertility, advanced maternal age infertility, single gene disorders (for PGT), HLA matching, chromosomal aneuploidies, recurrent oocyte maturation defects, and preimplantation embryo lethality — comprehensive care for international patients seeking best IVF and fertility treatment in Turkey.
3. How do I book an appointment with Prof. Semra KAHRAMAN?
Appointments with Prof. Dr. Dr. Semra Kahraman can be booked directly through the Cancer Rounds website or by contacting their international patient department for priority scheduling.
4. Can international patients receive treatment from Prof. Semra KAHRAMAN?
Yes. Cancer Rounds provides full assistance for international patients seeking treatment from Prof. Dr. Dr. Semra Kahraman, including medical visa invitation letters, airport transfers, and local accommodation coordination.
5. What support is available for international patients?
International patients benefit from a dedicated concierge service provided by Cancer Rounds, including language interpretation, financial counselling, and pre-travel virtual consultations to review medical records before arrival.
6. Does Prof. Semra KAHRAMAN offer second opinions for IVF Specialist cases?
Yes. Second opinion consultations can be arranged via Cancer Rounds for patients who wish to review their diagnosis or treatment plan with an expert IVF specialist in Istanbul, Turkey, especially for complex recurrent IVF failure, PGT indications, and rare genetic disorder cases.
