Prof. Semra KAHRAMAN

IVF Specialist

Prof. Semra KAHRAMAN

Professor

29+ years of experience

Associate Professor
Memorial Hospitals Group, İstanbul - Turkey

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    Areas of Expertise

    Prof. Semra KAHRAMAN

    Major Conditions Treated

    • Female Infertility
    • Male Infertility & Severe Male Factor
    • Recurrent Implantation Failure
    • Recurrent Pregnancy Loss
    • Low Ovarian Reserve
    • Poor Ovarian Response
    • Unexplained Infertility
    • Advanced Maternal Age Infertility
    • Single Gene Disorders (for PGT)
    • HLA Matching Requirements
    • Chromosomal Aneuploidies
    • Recurrent Oocyte Maturation Defects (OOMD)
    • Preimplantation Embryo Lethality (PREMBL)

    Sub-specialties

    • In Vitro Fertilization (IVF) & ICSI: Pioneer of ICSI in Turkey and comprehensive assisted reproductive technology — establishes her as a trusted IVF specialist specialist in Istanbul, Turkey.
    • Preimplantation Genetic Testing (PGT-A, PGT-M, PGT-SR): Pioneer of PGT for single gene disorders, HLA typing, and aneuploidy testing in Turkey.
    • Embryo Freezing / Vitrification: Pioneer of embryo freezing techniques in Turkey with multiple publications on vitrified blastocyst transfers.
    • Reproductive Genetics & Embryonic Stem Cells: First in Turkey to isolate and establish embryonic stem cell lines — for international patients seeking best IVF and fertility treatment in Turkey.
    • Time-Lapse Monitoring & AI-Assisted Embryo Selection: Research and clinical use of the CHLOE AI tool (Fairtility) for predicting euploidy.
    • Andrology & Surgical Sperm Extraction: First in Turkey to perform microinjection and surgical sperm extraction.

    Advanced Procedures & Treatments

    • In Vitro Fertilization (IVF)
    • Intracytoplasmic Sperm Injection (ICSI)
    • Intrauterine Insemination (IUI)
    • Embryo Vitrification & One-Step Warming
    • Oocyte Freezing / Egg Freezing
    • Fertility Preservation
    • Preimplantation Genetic Testing for Aneuploidy (PGT-A)
    • Preimplantation Genetic Testing for Monogenic Disorders (PGT-M)
    • Preimplantation Genetic Testing for Structural Rearrangements (PGT-SR)
    • HLA Typing for Embryos
    • Whole-Exome Sequencing (WES) for OOMD & PREMBL
    • Time-Lapse Embryo Monitoring (TLM)
    • AI-Assisted Embryo Selection (CHLOE Tool)
    • Surgical Sperm Extraction (TESE/MicroTESE)
    • Frozen-Thawed Single Blastocyst Transfer
    • Luteal Phase Support Protocols

    Qualifications & Credentials

    Medical Degrees

    • Medical Doctor Training — Hacettepe University Medical School, Ankara, Turkey, 1973–1981
    • Professional Training in Gynecology and Obstetrics — Faculty of Medicine, Ankara University, Ankara, Turkey, 1983–1989
    • Assistant Professorship — Faculty of Medicine, Ankara University, Ankara, Turkey, 1994
    • Full Professorship — Faculty of Medicine, Yeditepe University, Istanbul, Turkey, 2004

    Fellowships & Special Training

    • Haugesund Hospital Fertility Center & Oslo University Hospital Infertility Clinic, Norway, 1991–1992
    • Weill Cornell's Center for Reproductive Medicine, New York, USA, 1996–1997
    • Reproductive Genetic Institute (RGI), Chicago, USA, 1996–1997
    • Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Vilvoorde, Belgium, 1996–1997
    • Special Training — Cornell University IVF Center (USA), Rikshospitalet IVF Center (Norway)

    Certifications & Accreditations

    • Turkish Medical Association — Registered
    • ESHRE-Accredited Professional (Istanbul Memorial Hospital IVF Laboratory)
    • Full Professor — Faculty of Medicine, Yeditepe University, Istanbul
    • Memorial Şişli Hospital IVF Laboratory — TÜRKAK Accreditation per ISO 15189 standards (first in Turkey)

    Professional Experience

    Current Affiliation

    • Istanbul Memorial Hospital (Memorial Şişli Hospital), Istanbul, Turkey — Director of ART & Reproductive Genetics Unit, Since 2000
    • Memorial Health Group — Managing Director of IVF and Genetics Center
    • Memorial Şişli Hospital In Vitro Fertilization (IVF), Andrology and Genetics Center — Head

    Past Affiliations

    • Sevgi Hospital, Ankara — Director of ART (1993–2000)
    • Ankara University, Faculty of Medicine — Assistant Professor (1994)
    • Yeditepe University, Faculty of Medicine, Istanbul — Full Professor (2004)
    • Weill Cornell's Center for Reproductive Medicine, New York, USA — Fellowship (1996–1997)
    • Reproductive Genetic Institute (RGI), Chicago, USA — Fellowship (1996–1997)
    • Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Belgium — Fellowship (1996–1997)
    • Haugesund Hospital Fertility Center & Oslo University Hospital Infertility Clinic, Norway — Training (1991–1992)
    • Ankara University Faculty of Medicine — OB/GYN Speciality Training (1983–1989)
    • Hacettepe University Medical School — Medical Doctor Training (1973–1981)

    Academic & Research Roles

    • Full Professor — Faculty of Medicine, Yeditepe University, Istanbul (2004)
    • Past President — Preimplantation Genetic Diagnosis International Society (PGDIS)
    • Board Member — Preimplantation Genetic Diagnosis International Society
    • Author — 150+ scientific works and 738+ publications on infertility, IVF, and reproductive genetics
    • Invited Speaker and Chairman — Multiple international conferences including PGDIS, ASRM, ESHRE, and World Congress of Perinatal Medicine
    • Researcher — Oxidative stress in IVF, recurrent pregnancy loss, time-lapse monitoring, AI in embryo selection

    Key Achievements

    • 35+ years of clinical and academic experience in IVF and reproductive genetics
    • Pioneer of ICSI, embryo freezing, PGT for single gene disorders, HLA typing, and aneuploidy testing in Turkey
    • First in Turkey to isolate and establish embryonic stem cell lines
    • Past President of the PGT International Society
    • Director of ART & Reproductive Genetics Unit at one of Turkey's largest IVF programs since 2000
    • Published 150+ scientific works and 738+ publications on ResearchGate
    • Memorial Şişli Hospital IVF Laboratory — first in Turkey to receive TÜRKAK Accreditation per ISO 15189

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